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Michael D Threadgill Selected Research

5-aminoisoquinolinone

1/20155-Aminoisoquinolin-1-one (5-AIQ), a Water-Soluble Inhibitor of the Poly(ADP-Ribose)Polymerases (PARPs).
5/2005Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and the development of bleomycin-induced lung injury.
2/2005Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and secondary damage in experimental spinal cord trauma.
12/20045-Aminoisoquinolinone reduces colon injury by experimental colitis.
2/20045-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/reperfusion.

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Michael D Threadgill Research Topics

Disease

16Neoplasms (Cancer)
11/2019 - 06/2002
3Carcinoma (Carcinomatosis)
01/2015 - 05/2009
2Stroke (Strokes)
01/2015 - 02/2005
2Spinal Cord Injuries (Spinal Cord Injury)
01/2015 - 02/2005
2Colorectal Neoplasms (Colorectal Cancer)
05/2009 - 06/2002
2Inflammation (Inflammations)
05/2005 - 02/2005
2Edema (Dropsy)
05/2005 - 02/2005
1Prostatic Neoplasms (Prostate Cancer)
11/2019
1Pathologic Processes
09/2017
1Adenocarcinoma
01/2017
1Parkinson Disease (Parkinson's Disease)
01/2015
1Myocardial Infarction
01/2015
1Arthritis (Polyarthritis)
01/2015
1Multiple Sclerosis
01/2015
1Starvation
01/2015
1Periodontitis
01/2015
1Colonic Neoplasms (Colon Cancer)
12/2010
1Neoplasm Metastasis (Metastasis)
05/2009
1Sjogren-Larsson Syndrome
10/2007
1Nervous System Diseases (Neurological Disorders)
10/2007
1Tuberculosis (Tuberculoses)
07/2007
1Lung Injury
05/2005
1Body Weight (Weight, Body)
05/2005
1Myelitis
02/2005
1Wounds and Injuries (Trauma)
02/2005
1Necrosis
12/2004
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
12/2004
1Weight Loss (Weight Reduction)
12/2004
1Diarrhea
12/2004
1Colitis
12/2004
1Ischemia
02/2004
1Adenoma (Adenomas)
06/2002
1Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
06/2002
1Hemorrhage
06/2002

Drug/Important Bio-Agent (IBA)

8EnzymesIBA
04/2013 - 02/2004
6Racemases and Epimerases (Epimerases and Racemases)IBA
11/2019 - 07/2011
6Coenzyme A (CoA)IBA
11/2019 - 07/2011
6Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
12/2013 - 02/2004
55-aminoisoquinolinoneIBA
01/2015 - 02/2004
4DNA (Deoxyribonucleic Acid)IBA
05/2005 - 02/2004
3Ibuprofen (Motrin)FDA LinkGeneric
05/2017 - 07/2011
3Proteins (Proteins, Gene)FDA Link
07/2015 - 04/2013
3Poly(ADP-ribose) Polymerase InhibitorsIBA
05/2009 - 02/2005
2TankyrasesIBA
07/2015 - 12/2013
2Peroxidase (Myeloperoxidase)IBA
05/2005 - 02/2005
23-aminobenzamideIBA
05/2005 - 02/2005
1AndrogensIBA
11/2019
1Biomarkers (Surrogate Marker)IBA
11/2019
1Carboxylic AcidsIBA
11/2019
1Histones (Histone)IBA
09/2017
1Adenosine Diphosphate (ADP)IBA
09/2017
1Fatty Acids (Saturated Fatty Acids)IBA
05/2017
1Glucose (Dextrose)FDA LinkGeneric
01/2017
1Insulin (Novolin)FDA Link
01/2017
1ProdrugsIBA
07/2015
1Arginine (L-Arginine)FDA Link
01/2015
1AgarIBA
01/2015
1ADP Ribose Transferases (ADP Ribosyltransferase)IBA
01/2015
1bisbenzimide ethoxide trihydrochloride (Hoechst 33342)IBA
01/2015
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
04/2013
1EstersIBA
07/2011
1StilbenesIBA
12/2010
1Poly (ADP-Ribose) Polymerase-1IBA
09/2009
1NF-kappa B (NF-kB)IBA
05/2009
1LipidsIBA
03/2008
1Phytanic AcidIBA
03/2008
1long-chain-aldehyde dehydrogenaseIBA
10/2007
1Fatty AlcoholsIBA
10/2007
1Glycerol (Glycerine)FDA LinkGeneric
07/2007
1dihydrofolateIBA
07/2007
1Bleomycin (Blenoxane)FDA LinkGeneric
05/2005
1Annexin A5IBA
05/2005
13-nitrotyrosineIBA
05/2005
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
02/2005
1Uridine Triphosphate (UTP)IBA
02/2005
1DinitrobenzenesIBA
12/2004
12,4-dinitrofluorobenzene sulfonic acidIBA
12/2004
1Sulfonic AcidsIBA
12/2004
1Nitric Oxide Synthase (NO Synthase)IBA
09/2003
1Protein Isoforms (Isoforms)IBA
09/2003
1CurcuminIBA
06/2002

Therapy/Procedure

1Organ Transplantation
01/2015
1Laminectomy
02/2005
1Therapeutics
09/2003
1Boron Neutron Capture Therapy
01/2003
1Chemoprevention
06/2002